"Vice Premier Wang Yang is undertaking the visit to Pakistan on the directions of President Xi Jinping as a special gesture to participate in the 70th Independence Day Celebrations of Pakistan", reads the statement.
As a member of the Politburo of the Central Committee of the Communist Party, Wang is among the top and most senior leaders in China.
Wang Yong will call on President Mamnoon Hussain and Prime Minister Shahid Khaqan Abbasi and discuss promotion of bilateral relations.
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The visit to Pakistan and Nepal by the top Chinese official comes as India and China have been locked in a military standoff for almost two months at the strategic Doklam plateau in Bhutan.
The special visit of Vice Premier Wang underscores the close brotherly and cooperative ties between Pakistan and China and Beijing's strong political support for Islamabad.
In March, a contingent of the guard of honour of the three services of the Chinese People's Liberation Army (PLA) took part in the Pakistan military parade held in Islamabad to mark Pakistan Day.