Selecao had the ball in the back of the net after 20 minutes through Pepe, but the Video Assistant Referee deemed the goal offside just moments before Ronaldo had struck the crossbar.
But Portugal's talisman was at his best in an action-packed first half in his team's opening match, with hosts Russian Federation and New Zealand still to come in the group.
"It was not the result we wanted", the Portugal captain said.
A draw suits Mexico better as they prepare to face New Zealand next, but regardless, this was an enjoyable spectacle between two teams with ambitions of lifting the trophy and it will serve as a welcome tonic to the watching Infantino.
"It is a little hard for the players", Chile coach Juan Antonio Pizzi said.
Cristiano Ronaldo skips post-match press conference after Portugal draw
A late header from Hector Moreno salvaged a 2-2 draw for Mexico in their opening FIFA Confederations Cup match against Portugal . Portugal players will wear black armbands against Mexico in the today to honour compatriots that passed away from forrest fires.
Silva, who has just moved from FC Porto to AC Milan in a transfer worth almost 40 million euros, has scored seven goals in eight games since his debut with the national team in a friendly against Gibraltar in September.
Federation Internationale de Football Association is trialing the use of video assistants and wants them to be used at next year's World Cup in Russia.
Portugal thought they had the lead after Pepe scrambled home from close range, but the VAR system ruled him offside. "It was a fair result for how the teams played".
Of greater outcome was the astute piece of vision later in the first half, which set up Ricardo Quaresma for a strike that counted, even if the speed and power that used to characterize Ronaldo initially failed him. Juan Carlos Osorio also has a plethora of talent on his squad with players like Diego Reyes, Marco Fabian, Andres Guardado, Carlos Vela and "Chicharito" Hernandez.
"We still believe in qualification, we have great possibilities, because there are still two games left. We're very happy with this first game".
(AP Photo/Martin Meissner). Portugal's Cristiano Ronaldo looks down in the shadow during a training session at the Arena in Kazan, Russia, on Saturday, June 17, 2017. This tournament will be hard for them to win with a lot of talent in the likes of Germany here but still I will expect them to compete in this game.